ACS_the Journal of Physical Chemistry Letters


ACS_the Journal of Physical Chemistry Letters

September 30, 2021

Volume 12, Issue 38

Pages 9188-9412

Adsorbed Water Structure on Acrylate-Based Biocompatible Polymer Surface

  • Saptarsi Mondal
  • Jooyoun Kang
  • Kwanghee Park
  • Jong Min Lim
  • Jeong-Hyon Ha
  • Kyungwon Kwak
  • Minhaeng Cho

The role of water in the excellent biocompatibility of the acrylate-based polymers widely used for antibiofouling coating material has been realized previously. Here, we report femtosecond mid-infrared pump–probe spectroscopy of the OD stretch band of HOD molecule adsorbed on highly biocompatible poly(2-methoxyethyl) acrylate [PMEA] and poorly biocompatible poly(2-phenoxyethyl) acrylate [PPEA], both of which reveal that there are two water species with significantly different vibrational lifetime. PMEA interacts more strongly with water than PPEA through the H-bonding interaction between carbonyl (C═O) and water. The vibrational lifetime of the OD stretch in PPEA is notably longer by factors of 3 and 7 than those in PMEA and bulk water, respectively. The IR-pump visible-probe photothermal imaging further unravels substantial spatial overlap between polymer CO group and water for hydrated PMEA and a significant difference in surface morphology than those in PPEA, which exhibits the underlying relationships among polymer–water interaction, surface morphology, and biocompatibility.

The Journal of Physical Chemistry Letters | Vol 12, No 38 (

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